Marcela Dávila López

Curriculum Vitae

EDUCATION

2011 - current Postdoc, Göteborg Universitet, Sweden
2007 - 2011 PhD. In Bioinformatics, Göteborg Universitet, Sweden
Evolution of proteins and non-coding RNA genes studied with comparative genomics
2004 - 2005 MSc. In Bioinformatics, Chalmers Tekniska Högskola, Sweden
Computational analysis of the protein subunits of the ribonucleases P and MRP- Identification of novel protein relationships
2002 - 2004 MSc. in Chemical Engineering, Universidad de Guadalajara, Mexico
Design, construction and validation of a capillar rheometer and its aplication to Dairy Industry
1996 - 2001 BSc. In Chemical and Biological Analysis, Universidad Autónoma de Aguascalientes, Mexico

WORK EXPERIENCE

2013 Manager, Bioinformatics Core Facility, University of Gothenburg.
Lecturer - Lab supervisor, University of Gothenburg. Academic assistance to doctoral students covering NGS data analysis and Introduction to bioiformatics
2011 Bioinformatics Data Analyst, Genomics Core Facility, University of Gothenburg.
Lecturer - Lab supervisor, University of Gothenburg. Academic assistance to doctoral students covering NGS data analysis and Introduction to bioiformatics
2010 Lab instructor, University of Gothenburg. Academic assistance to medical students covering computational practicals
Lecturer - Lab supervisor, University of Gothenburg. Academic assistance to doctoral students covering Introduction to bioiformatics
2009 Lab instructor, University of Gothenburg. Academic assistance to medical, odontology and pharmacist students covering computational and wet lab practicals
Lecturer - Lab supervisor, University of Gothenburg. Academic assistance to doctoral students covering Introduction to bioiformatics
Lecturer - Lab supervisor, Chalmers University of Technology. Academic assistance to IMP Bioinformatics and systems biology students covering Introduction to bioinformatics and Sequence bioinformatics courses.
2008 Lecturer - Lab supervisor, Chalmers University of Technology. Academic assistance to IMP Bioinformatics and systems biology students covering Introduction to bioinformatics and Sequence bioinformatics courses.
2007 Lab supervisor, Chalmers University of Technology. Academic assistance to IMP Bioinformatics and systems biology students covering Introduction to bioinformatics and Sequence bioinformatics courses.
2006 Lab supervisor, Chalmers University of Technology. Academic assistance to IMP in Bioinformatics students covering Introduction to bioinformatics and Sequence information courses.
2004 Professor, University of Guadalajara. Academic assessory to Chemical Engineering students.
2004 Professor, University of Guadalajara. Academic assessory to Chemical Engineering students.
2003 Educative Assistant, University of Guadalajara. Academic assistance to Chemical Engineering students.
2002 Technician, Milk Union of Juarez Farmers. Performance of physicochemical and microbiologic analysis to raw milk.
2001 Technician, University of Aguascalientes. Crystal material preparation (media and solutions as well) for practicals. Performance of microbiological analysis of water and food.
2000 Research Assistant, University of Aguascalientes. Performance of experiments concerning stabilization lagoons of acclimated biomass and its capacity of biodegradation.
1999 Technician, General Department of Justice of Aguascalientes. Performance of tanatologic and toxicologic studies and those related with guns, sexual assaults and spots.
English Teacher, Several Elementary and Junior high schools in Mexico.

PUBLICATIONS

  1. Sofou, K., et al. Whole exome sequencing reveals mutations in NARS2 and PARS2, encoding the mitochondrial asparaginyl-tRNA synthetase and prolyl-tRNA synthetase, in patients with Alpers Syndrome. Molecular Genetics & Genomic Medicine, 2014 (in press)
  2. Einarsdottir B.O., et al. Melanoma patient-derived xenografts accurately models the disease and develop fast enough to guide treatment decisions. OnctoTarget,September 08, 2014
  3. Banyai, G. et al. Mediator can regulate mitotic entry and direct periodic transcription in fission yeast.. Mol Cell Biol. 2014 Aug 25. pii: MCB.00819-14
  4. Nilsson, J. et al. Polyglucosan body myopathy caused by defective ubiquitin ligase RBCK1. Ann Neurol. 2013 Dec;74(6):914-9. doi: 10.1002/ana.23963
  5. Terzioglu, M. et al. MTERF1 Binds mtDNA to Prevent Transcriptional Interference at the Light-Strand Promoter but Is Dispensable for rRNA Gene Transcription Regulation Cell Metab 17, 618-626, 2013
  6. Bhadury, J. et al. Identification of tumorigenic and therapeutically actionable mutations in transplantable mouse tumor cells by exome sequencing Oncogenesis. 2013 Apr 15;2:e44. doi: 10.1038/oncsis.2013.8.
  7. Carlsten, JO. et al. Mediator Promotes CENP-A Incorporation at Fission Yeast Centromeres. Mol Cell Biol. 2012 Oct;32(19):4035-43. doi: 10.1128/MCB.00374-12
  8. Szilagyi, Z,. et al. Cyclin-dependent kinase 8 regulates mitotic commitment in fission yeast. Mol Cell Biol. 2012. Jun;32(11):2099-109.
  9. Zhu, X. et al. Histone modifications influence mediator interactions with chromatin. Nucleic Acids Res. 2011 Oct;39(19):8342-54.
  10. Davila Lopez and T. Samuelsson. eGOB: eukaryotic Gene Order Browser. Bioinformatics, 2011. 27(8): p. 1150-1. eGOB: eukaryotic Gene Order Browser. Bioinformatics, 2011. 27(8): p. 1150-1. eGOB
  11. Davila Lopez, M., J.J. Martinez Guerra, and T. Samuelsson, Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes. PLoS One, 2010. 5(5): p. e10654. Supplemental data
  12. Davila Lopez, M., M.A. Rosenblad, and T. Samuelsson, Conserved and variable domains of RNase MRP RNA. RNA Biol, 2009. 6(3): p. 208-20.
  13. Davila Lopez, M., M.A. Rosenblad, and T. Samuelsson, Computational screen for spliceosomal RNA genes aids in defining the phylogenetic distribution of major and minor spliceosomal components. Nucleic Acids Res, 2008. 36(9): p. 3001-10. Supplemental data
  14. Davila Lopez, M. and T. Samuelsson, Early evolution of histone mRNA 3' end processing. RNA, 2008. 14(1): p. 1-10. Supplemental data
  15. Rosenblad, M. A., M. D. Lopez, P. Piccinelli, and T. Samuelsson. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Nucleic Acids Res, 2006. 34(18): p. 5145-56. Web supplement

RECENT PARTICIPATIONS

2011 Sep Mitochondrial Dynamics: from mechanism to disease, Sardinia, Italy
Participation with "Bioinformatics analysis of NGS data Identifying novel mutations causing mitochondrial diseases" Abstract
2010 Mar 10th Swedish Bioinformatics Workshop for PhD students and Postdocs, Göteborg, Sweden (Best poster award)
Participation with "Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes" Abstract
2009 Mar 9th Swedish Bioinformatics Workshop for PhD students and Postdocs, Umeå, Sweden
Participation with "Non-random gene order in Eukaryotes" Abstract
2008 Jul 13th Annual Meeting of the RNA Society, Berlin, Germany
Participation with "Computational screen for spliceosomal RNA genes aids in defining the phylogenetic distribution of themajor and minor spliceosomal components"
Feb 8th Swedish Bioinformatics Workshop for PhD students and Postdocs, Uppsala, Sweden
Participation with "Towards a complete inventory of spliceosomal RNAs by bioinformatics methods" Abstract
2007 Nov Biomedicine day, Göteborg, Sweden
Participation with "Towards a complete inventory of spliceosomal RNAs by bioinformatics methods"
Jul 15th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) & 6th European Conference on Computational Biology (ECCB), Vienna, Austria
Participation with "A histone 3' end processing machinery in protozoa" Abstract
Jun 9th International Northern European Bioinformatics Conference,Umeå, Sweden
Participation with "A histone 3' end processing machinery in protozoa"
2006 Nov 7th Swedish Bioinformatics Workshop for PhD students and Postdocs, Stockholm, Sweden
Participation with "Analysis of the protein subunits of the ribonucleases P and MRP - Identification of novel protein relationships" Abstract
2005 Nov 6th Swedish Bioinformatics Workshop for PhD students and Postdocs, Göteborg, Sweden
Participation with "Analysis of the protein composition of RNases P and MRP"
2004 May XXV National Meeting of the AMIDIQ, A.C., Puerto Vallarta, Mexico
Participation with "Capillar rheometry of comercial yoghurt"
2003 May XXIV National Meeting of the AMIDIQ, A.C., Ixtapa, Mexico
Participation with "Design, construction and validation of a capillar rheometer"

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APR 2013